Vitamin K1 (phylloquinone), K2 (menaquinone)

Vitamin K is an essential micronutrient, sometimes referred to as a coagulative vitamin. Vitamin K includes two natural forms - vitamin K1 (phylloquinone) and vitamin K2 (menaquinone).

Maybe you are interested in a function and behaviour of vitamin K. These vitamins act as coenzymes in the synthesis of some biologically active proteins involved in blood clotting. They are also necessary for the bone and tooth strength and also used in other important biological processes (1).

Phylloquinone and menaquinone are responsible for body regulation of calcium. Vitamin K1 is processed by liver and then it is followed by protein-calcium binding.

Vitamin K2 is responsible for activation of proteins, which are responsible for regulation of calcium and its secretion.

According to laboratory analysis was in Mana's substances detected vitamin K2 type MK7. Vitamin K2 has been found out as the first naturally consumption in this type of nutritional food.

There is evidence that vitamin K contributes to normal blood clotting and to the maintenance of normal bones. 5 servings of Mana or Mana Drink contains 75 µg of vitamin K1 (phylloquinone) and 255 µg of vitamin K2 (menaquinone type 7).

Enjoy Mana as part of your varied and balanced diet and healthy lifestyle. Mana is suitable for all healthy adults.


Sources of informations:


1. Brini M., Calì T., Ottolini D., Carafoli E. (2013) Intracellular Calcium Homeostasis and Signaling. In: Banci L. (eds) Metallomics and the Cell. Metal Ions in Life Sciences, vol 12. Springer, Dordrecht
online: https://link.springer.com/chapter/10.1007%2F978-94-007-5561-1_5

Vitamin and mineral requirements in human nutrition: report of a joint FAO/WHO expert consultation, Bangkok, Thailand, 21–30 September 1998, online: http://apps.who.int/iris/bitstream/handle/10665/42716/9241546123.pdf;jsessionid=B2002456BACDAF0BF79173EFFC7D8A3B?sequence=1


Clinical Studies:

http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2009.1228/epdf

Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats.

H. M. H. Spronk, B. A. M. Soute, L. J. Schurgers, H. H. W. Thijssen, J. G. R. De Mey, C. Vermeer

J Vasc Res. 2003 Nov-Dec; 40(6): 531–537.  Published online 2003 Dec 3. doi: 75344

online: https://www.ncbi.nlm.nih.gov/pubmed/14654717